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Our symptoms are typically treatment resistant. Just as isotretinoin’s renowned anti-acneic effects are known to last for life for some people, its potential sexual side effects sometimes do also. Others have noted that it gets gradually worse on treatment and then continues to worsen when treatment is stopped. The problem can then significantly and rapidly worsen when isotretinoin is stopped. The sexual symptoms may initially be relatively mild. Our problems closely resemble PFS (Post-Finasteride Syndrome) and PSSD ( Post-SSRI Sexual Dysfunction).Īfter going on treatment many people get mild-to-debilitating anhedonia, anxiety and fatigue. Sexual dysfunction has been my lot in life since taking Accutane over 14 years ago, and as noted, I am far from alone. Stories of sexual side effects have played out in doctor’s offices and online forums past and present, including the once active website and the now popular website.

When people finally decide to seek medical intervention for these symptoms, many encounter fierce resistance from dermatologists and general practitioners when they explain that isotretinoin played a role in their life-altering condition, who can point to the fact that sexual complications are not listed on isotretinoin’s laundry list of side effects. Sometimes, they discontinue isotretinoin early because of sexual problems only to find that the problems get worse and persist indefinitely after taking the last pill. Or they continue to expect those side effects to abate after cessation of the drug. Often these affected young men and women, many in their teens and early 20s, cannot overcome their embarrassment to report sexual side effects while taking the drug.

There are an ever-increasing and disturbing number of young people claiming their sex lives have been permanently ruined from taking the acne drug, isotretinoin, commonly referred to by its former brand-name, Accutane.

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